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Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery …

2020

BACKGROUND: The aim of this study was to evaluate and compare the postoperative effect of a topic gel containing chlorhexidine, chitosan, allantoine and dexpanthenol versus a placebo for pain and inflammation control after third molar surgery. MATERIAL AND METHODS: A gel combining 0.2% chlorhexdine, 0.5% chitosan, 5% dexpanthenol, 0.15% allantoin and 0.01% sodium saccharin was selected for this split mouth randomized controlled and double-blind trial including 36 patients with bilaterally and symmetrically impacted lower third molars. The teeth (n=72) were randomly divided into two groups before surgical removal: control group (CG; in which a placebo was given) and experimental group (EG). …

MolarallantoinTrismusPantothenic Acidsurgerychemistry.chemical_compound0302 clinical medicineEdemaMedicinepainProspective StudiesBIOADHESIVE GELAllantoinPain PostoperativeChlorhexidinechlorhexidineTooth Impactedpostoperative wound healing:CIENCIAS MÉDICAS [UNESCO]Dry socketIThird molarAnesthesiaUNESCO::CIENCIAS MÉDICASOral Surgerymedicine.symptomDexpanthenolLife Sciences & Biomedicinemedicine.druggeldexpanthenolEXTRACTIONPlacebo03 medical and health sciencesAllantoinDouble-Blind MethodDentistry Oral Surgery & MedicineHumansGeneral DentistryInflammationChitosanScience & Technologybusiness.industryResearchINTRAALVEOLAR PLACEMENTChlorhexidine030206 dentistrymedicine.diseaseALVEOLAR OSTEITISPREVENTIONClinical trialOtorhinolaryngologychemistryTooth ExtractionMolar ThirdTrismusSurgerychitosanbusiness
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